Epoxy resins and occupational sensitisation

Epoxy systems can sensitise skin before curing. Prevention must consider the resin, hardener, additives and the way the product is applied.

In brief

Epoxy systems can sensitise skin before curing. Prevention must consider the resin, hardener, additives and the way the product is applied.

Contents
  1. A system rather than one substance
  2. What sensitisation means
  3. Tasks in which contact is easily missed
  4. Reduce exposure before relying on gloves
  5. Compatible protection and cleaning
  6. What changes after curing
  7. Related concepts
  8. References

A–Z dictionary →

A system rather than one substance

Epoxy products are used in adhesives, coatings and composite materials. They commonly combine a resin with a hardener and may contain diluents, fillers or solvents. Each component can contribute different hazards. Assessing only the container labelled resin leaves part of the process unexamined. Review safety data sheets for every component together with the manufacturer’s mixing and application instructions for the actual product system.

What sensitisation means

Some substances in the system can cause allergic contact dermatitis as well as irritation. Once sensitised, a person may react to small amounts of the responsible agent. The appearance of a rash does not always distinguish allergy from irritation. Symptoms require professional assessment; tolerance must not be tested by applying product to the skin, and a previously uneventful exposure is not an indefinite guarantee of safety.

Tasks in which contact is easily missed

Preparation, transfer, manual application and tool cleaning deserve specific attention. Contact can also occur through contaminated handles, gloves, phones or clothing. Spraying introduces inhalation of aerosol, while certain components or conditions also generate vapours. A small, occasional repair may need different controls from an automated production line, even when it uses the same commercial product. Include waste handling and cleanup in the assessment.

Reduce exposure before relying on gloves

Consider less hazardous formulations and application methods, contained dosing and tools that separate skin from the product. Organise areas and containers for contaminated materials. Dermal exposure assessment helps review direct and indirect contact. Design ventilation around what may be released; an open window does not demonstrate adequate control of spraying. Instructions should address the real sequence of work rather than only the mixing stage.

Compatible protection and cleaning

Select gloves using resistance information for the components handled and the actual duration of the task. Colour or disposability alone is not a sufficient selection criterion. Avoid contamination during removal and provide replacement gloves. Solvents must not be used to clean skin. Plan suitable eye protection, clothing and cleaning methods consistent with the safety data sheet, including the handling of contaminated tools and waste.

What changes after curing

Curing transforms the system, but should not be assumed complete merely because a surface feels dry. Follow the manufacturer’s specified conditions. Subsequent sanding or machining introduces dust and other hazards requiring separate assessment. Recurrent dermatitis calls for a review of components, contamination and tasks with occupational health. Changing brand does not guarantee removal of the allergen when different formulations contain the same sensitising substances.

References

  1. CPWR: Epoxy Resin Systems 2023. Official source
  2. NIOSH: Skin exposures and effects. Official source
  3. NIOSH: Preventing skin disease. Official source
  4. Epoxy Europe: Epoxy resins and curing agents. Official source

Editorial information

Publication date: 2 November 2026.

Editorial responsibility: Sabentis Editorial Team.

Author: Pablo RodríguezLinkedIn

Executive Vice President of the ORP International Foundation and Chief Financial Officer of Sabentis.

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