Respiratory sensitisation at work

Respiratory sensitisation is the development of a hypersensitivity response to an agent. After sensitisation, a person may have respiratory reactions to later exposures, even small ones.

In brief

Respiratory sensitisation is the development of a hypersensitivity response to an agent. After sensitisation, a person may have respiratory reactions to later exposures, even small ones.

Contents
  1. Sensitisation and irritation are different
  2. Agents and tasks needing attention
  3. Why early action matters
  4. Control before relying on a mask
  5. Health surveillance linked to risk
  6. Process improvement example
  7. Related concepts
  8. References

A–Z dictionary →

Sensitisation and irritation are different

Irritation can result from a substance’s direct action on the airways without sensitisation. Hypersensitivity involves a different response and may develop after a symptom-free exposure period. Moreover, sensitised people do not all develop the same disease or respond identically to later contact.

Agents and tasks needing attention

Flours, certain isocyanate products, enzymes, laboratory animals and some substances used in cleaning or manufacturing may be involved. Processes and safety data sheets are reviewed, including H334 where relevant. Absence of a labelled container does not rule out risk: some exposures arise from processes or biological materials.

Why early action matters

Cough, wheezing, chest tightness or nasal symptoms related in time to work need medical assessment. They may occur after the shift. The occupational asthma article addresses the disease; here the focus is the sensitisation mechanism and prevention. Cause is not confirmed through a symptom list or by independently exposing the person again.

Control before relying on a mask

Elimination or substitution where feasible, closed processes and emission extraction take priority. Cleaning and maintenance also matter: dispersing dust can spread exposure to other tasks. Respiratory protection requires appropriate selection and use but does not replace those controls. For sensitised people, exposure management must follow individual professional assessment.

Health surveillance linked to risk

Surveillance must be organised by competent healthcare staff using criteria related to the agents present. A clear channel is needed for reporting symptoms without waiting for the next scheduled review. Findings inform control review while preserving confidentiality. Surveillance alone does not establish that a job is safe or replace occupational hygiene assessment.

Process improvement example

In a hypothetical example, a bakery receives reports of symptoms during bag emptying. Dust generation, extraction and cleaning are reviewed, and medical assessment facilitated. The response is not limited to issuing masks or informally moving the person who complains: the task is investigated to protect the rest of the team too.

References

  1. HSE. Asma laboral y sensibilizantes respiratorios. Official source
  2. HSE. G402: vigilancia de la salud frente al asma ocupacional. Official source

Editorial information

Publication date: 1 November 2026.

Editorial responsibility: Sabentis Editorial Team.

Author: Pablo RodríguezLinkedIn

Executive Vice President of the ORP International Foundation and Chief Financial Officer of Sabentis.

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